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FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 31-35)

Details for Product anti-FLT1 Antibody No. ABIN871731, Supplier: Login to see
Antigen
  • FLT1
  • VEGFR1
  • AI323757
  • Flt-1
  • VEGFR-1
  • sFlt1
  • FLT
  • FLT-1
  • flt1b
Alternatives
anti-Human FLT1 antibody for Enzyme Immunoassay
Epitope
AA 31-35
30
19
13
13
9
8
6
5
5
5
5
5
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
241
73
61
11
4
2
2
2
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
182
86
7
4
2
1
Clonality
Polyclonal
Conjugate
This FLT1 antibody is un-conjugated
15
10
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
163
132
58
49
40
22
22
18
12
12
11
5
2
2
1
1
1
1
1
Supplier
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Immunogen Peptide sequence around AA 31-35 (D-P-E-L-S) derived from Human VEGFR1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Specificity The antibody detects endogenous level of total VEGFR1 protein.
Purification Affinity purified
Alternative Name VEGFR1 (FLT1 Antibody Abstract)
Background Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Molecular Weight 180 kDa
Gene ID 2321
NCBI Accession NP_002010
UniProt P17948
Pathways RTK Signaling
Application Notes Western blotting: 1:500-1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).