CCDC39 antibody (AA 651-750)

Catalog No. ABIN872343

Product Details anti-CCDC39 Antibody

Target: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Binding Specificity: AA 651-750

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC39 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC39

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CCDC39

Target: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Alternative Name: CCDC39 (CCDC39 Products)

Synonyms: 4921507O14Rik antibody, AI447426 antibody, AI844750 antibody, D3Ertd789e antibody, b2b1304Clo antibody, b2b1735Clo antibody, RGD1306277 antibody, CILD14 antibody, FAP59 antibody, coiled-coil domain containing 39 antibody, flagellar associated protein antibody, Ccdc39 antibody, CCDC39 antibody, ccdc39 antibody, FAP59 antibody

Background:

Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.

Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

Gene ID: 339829