GIMAP2 antibody (AA 21-120)

Catalog No. ABIN872766

Product Details anti-GIMAP2 Antibody

Target: GIMAP2 (GTPase, IMAP Family Member 2 (GIMAP2))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIMAP2 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIMAP2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
other()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GIMAP2

Target: GIMAP2 (GTPase, IMAP Family Member 2 (GIMAP2))

Alternative Name: Gimap2 (GIMAP2 Products)

Synonyms: GIMAP5 antibody, HIMAP2 antibody, IMAP2 antibody, GTPase, IMAP family member 2 antibody, GIMAP2 antibody

Background:

Synonyms: GTPase, IMAP family member 2, HIMAP2, IMAP2, Immunity associated protein 2, GIMA2_HUMAN.

Background: The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP2 (GTPase IMAP family member 2), also known as IMAP2 (immunity-associated protein 2) or HIMAP2, is a 337 amino acid multi-pass membrane protein that is encoded by a gene located on human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5 % of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Gene ID: 26157

UniProt: Q9UG22