RNLS antibody (AA 201-300)

Catalog No. ABIN872790

Product Details anti-RNLS Antibody

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Binding Specificity: AA 201-300

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNLS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Renalase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Alternative Name: Renalase (RNLS Products)

Synonyms: zgc:92286 antibody, C10orf59 antibody, RENALASE antibody, 6530404N21Rik antibody, AI452315 antibody, AW060440 antibody, RGD1309804 antibody, renalase, FAD dependent amine oxidase antibody, renalase, FAD-dependent amine oxidase antibody, RNLS antibody, rnls antibody, Rnls antibody

Background:

Synonyms: C10orf59, RENALASE, Monoamine oxidase-C, MAO-C, alpha-NAD(P)H oxidase/anomerase, RNLS

Background: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Gene ID: 55328

UniProt: Q5VYX0