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MAP2K6 antibody (pSer207) (Alexa Fluor 488)

MAP2K6 Reactivity: Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN874786
  • Target See all MAP2K6 Antibodies
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Binding Specificity
    • 18
    • 15
    • 11
    • 9
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer207
    Reactivity
    • 73
    • 63
    • 38
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 87
    • 6
    • 2
    Rabbit
    Clonality
    • 89
    • 6
    Polyclonal
    Conjugate
    • 47
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MAP2K6 antibody is conjugated to Alexa Fluor 488
    Application
    • 82
    • 41
    • 26
    • 26
    • 16
    • 14
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human MEK6 around the phosphorylation site of Ser207
    Isotype
    IgG
    Top Product
    Discover our top product MAP2K6 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Alternative Name
    MEK6 (MAP2K6 Products)
    Synonyms
    MAPKK6 antibody, MEK6 antibody, MKK6 antibody, PRKMK6 antibody, SAPKK-3 antibody, SAPKK3 antibody, Mkk6 antibody, Prkmk6 antibody, MKK3 antibody, map2k3 antibody, zMKK3 antibody, map2k6 antibody, mitogen-activated protein kinase kinase 6 antibody, mitogen-activated protein kinase kinase 6 L homeolog antibody, MAP2K6 antibody, Map2k6 antibody, map2k6 antibody, map2k6.L antibody
    Background

    Synonyms: MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK6, MEK6, Mitogen Activated Protein Kinase Kinase 6, MKK 6, MKK6, PRKMK6, SAPKK3, Dual specicity mitogen activated protein kinase kinase 6, MKK 6, Dual specicity mitogen activated protein kinase kinase 6, EC 2.7.12.2, MP2K6_HUMAN.

    Background: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

    Gene ID
    5608
    Pathways
    MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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