TWF1 antibody (pTyr321) (Alexa Fluor 350)

Catalog No. ABIN879487

Product Details anti-TWF1 Antibody (Alexa Fluor 350)

Target: TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))

Binding Specificity: pTyr321

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWF1 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human TWF1 around the phosphorylation site of Tyr321

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TWF1

Target: TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))

Alternative Name: PTK9 (TWF1 Products)

Synonyms: A6 antibody, PTK9 antibody, Ptk9 antibody, twinfilin antibody, ptk9 antibody, twf1 antibody, wu:fd02b03 antibody, zgc:65922 antibody, DKFZp469O1925 antibody, CG3771 antibody, Dmel\\CG3771 antibody, EG:9D2.3 antibody, zgc:92472 antibody, twinfilin actin binding protein 1 antibody, twinfilin actin-binding protein 1a antibody, twinfilin actin binding protein 1 S homeolog antibody, twinfilin-1 antibody, hypothetical protein antibody, Twinfilin-1 antibody, twinfilin actin-binding protein 1 antibody, CG3771 gene product from transcript CG3771-RC antibody, twinfilin actin-binding protein 1b antibody, TWF1 antibody, Twf1 antibody, twf1a antibody, twf1.S antibody, PTRG_09288 antibody, PGTG_01788 antibody, Tsp_02530 antibody, twf1 antibody, a6 antibody, twf1b antibody

Background:

Synonyms: PTK9 Tyr321, PTK9 Y321, p-PTK9 Tyr321, p-TWF1Y321, A6, A6 protein tyrosine kinase, Protein A6, Protein tyrosine kinase 9, PTK9, PTK9 protein tyrosine kinase 9, TWF 1, TWF1, Twinfilin 1, Twinfilin actin binding protein, homolog 1, Twinfilin, Twinfilin, actin-binding protein, homolog 1 Drosophila, Twinfilin, Drosophila, homolog of, 1, TWF1_HUMAN, Twinfilin-1.

Background: PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.

Gene ID: 5756

Pathways: Regulation of Actin Filament Polymerization, Maintenance of Protein Location