ASB2 antibody (AA 501-587) (Alexa Fluor 350)

Catalog No. ABIN883750

Product Details anti-ASB2 Antibody (Alexa Fluor 350)

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Binding Specificity: AA 501-587

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB2 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASB2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ASB2

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Alternative Name: ASB2 (ASB2 Products)

Synonyms: ASB-2 antibody, 1110008E15Rik antibody, ASB2 antibody, asb2 antibody, zgc:77223 antibody, ankyrin repeat and SOCS box containing 2 antibody, ankyrin repeat and SOCS box-containing 2 antibody, ankyrin repeat and SOCS box containing 2b antibody, ASB2 antibody, Asb2 antibody, asb2b antibody

Background:

Synonyms: Ankyrin repeat and SOCS box 2 containing protein, Ankyrin repeat and SOCS box containing 2, Ankyrin repeat and SOCS box containing protein 2, Ankyrin repeat containing protein ASB2.ASB2_HUMAN

Background: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Gene ID: 51676