ASB2 antibody (Ankyrin Repeat and SOCS Box-Containing 2) (Alexa Fluor 350)

Details for Product anti-ASB2 Antibody No. ABIN883750, Supplier: Log in to see
Antigen
  • ASB2
  • ASB-2
  • 1110008E15Rik
  • ankyrin repeat and SOCS box containing 2
  • ankyrin repeat and SOCS box-containing 2
  • ASB2
  • Asb2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
49
17
17
Host
Rabbit
41
8
Clonality
Polyclonal
Conjugate
This ASB2 antibody is conjugated to Alexa Fluor 350
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
27
21
12
5
5
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from human ASB2
Isotype IgG
Purification Purified by Protein A.
Alternative Name Asb2 (ASB2 Antibody Abstract)
Background

The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Synonyms: Ankyrin repeat and SOCS box 2 containing protein, Ankyrin repeat and SOCS box containing 2, Ankyrin repeat and SOCS box containing protein 2, Ankyrin repeat containing protein ASB2.ASB2_HUMAN

Gene ID 51676
Research Area Chromatin and Nuclear Signaling, Cell Cycle, Transcription Factors
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
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