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CIDEC antibody (AA 101-200) (FITC)

CIDEC Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN890705
  • Target See all CIDEC Antibodies
    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
    Binding Specificity
    • 14
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivity
    Human, Mouse, Rat
    Host
    • 36
    • 5
    • 1
    Rabbit
    Clonality
    • 39
    • 3
    Polyclonal
    Conjugate
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CIDEC antibody is conjugated to FITC
    Application
    • 39
    • 22
    • 12
    • 12
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificity
    Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology.
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CIDEC
    Isotype
    IgG
    Top Product
    Discover our top product CIDEC Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
    Alternative Name
    CIDEC (CIDEC Products)
    Synonyms
    fsp27 antibody, cide-3 antibody, MGC89274 antibody, cidec antibody, MGC82483 antibody, CIDEC antibody, fd36c01 antibody, wu:fd36c01 antibody, zgc:153033 antibody, CIDE-3 antibody, CIDE3 antibody, FPLD5 antibody, FSP27 antibody, Fsp27 antibody, CIDE-C antibody, cell death inducing DFFA like effector c antibody, cell death inducing DFFA like effector c S homeolog antibody, cell death-inducing DFFA-like effector c antibody, Cell death activator CIDE-3 antibody, cidec antibody, cidec.S antibody, CIDEC antibody, Cidec antibody
    Background

    Synonyms: CIDE3, FPLD5, FSP27, CIDE-3, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC

    Background: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

    Gene ID
    63924
    UniProt
    Q96AQ7
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