CYP11B1 antibody (AA 301-400) (Alexa Fluor 488)

Catalog No. ABIN893113

Product Details anti-CYP11B1 Antibody (Alexa Fluor 488)

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Binding Specificity: AA 301-400

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP11B1 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYP11B1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CYP11B1

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Alternative Name: CYP11B1 (CYP11B1 Products)

Synonyms: CPN1 antibody, CYP11B antibody, FHI antibody, P450C11 antibody, AA389061 antibody, Cyp11b antibody, Cyp11b-1 antibody, Cp11ba antibody, RATCP11BA antibody, P450c11 antibody, cytochrome P450, family 11, subfamily B, polypeptide 1 antibody, cytochrome P450 family 11 subfamily B member 1 antibody, cytochrome P450, family 11, subfamily b, polypeptide 1 antibody, cytochrome P450, subfamily XI B, polypeptide 1 antibody, CYP11B1 antibody, Cyp11b1 antibody

Background:

Synonyms: FHI, CPN1, CYP11B, P45C11, Cytochrome P45 11B1, mitochondrial, CYPXIB1, Cytochrome P-45c11, Cytochrome P45C11, Steroid 11-beta-hydroxylase, CYP11B1, S11BH

Background: Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P45 XIB.

Gene ID: 1584

UniProt: P15538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis