FGF6 antibody (AA 110-208) (Alexa Fluor 488)

Catalog No. ABIN897117

Product Details anti-FGF6 Antibody (Alexa Fluor 488)

Target: FGF6 (Fibroblast Growth Factor 6 (FGF6))

Binding Specificity: AA 110-208

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF6 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FGF6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FGF6

Target: FGF6 (Fibroblast Growth Factor 6 (FGF6))

Alternative Name: FGF6 (FGF6 Products)

Synonyms: FGF6 antibody, hst2 antibody, fgf-6 antibody, hbgf-6 antibody, HBGF-6 antibody, HST2 antibody, Fgf-6 antibody, HSTF-2 antibody, fgf4 antibody, fgf6 antibody, fibroblast growth factor 6 antibody, fibroblast growth factor 6a antibody, FGF6 antibody, fgf6 antibody, Fgf6 antibody, fgf6a antibody

Background:

Synonyms: FGF 6, FGF6, FGF-6, Fibroblast growth factor 6, Fibroblast growth factor 6 precursor, HBGF 6, HBGF6, HST 2, HST2.

Background: FGF6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. The FGF6 gene displays oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.

Gene ID: 2251

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway