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INSRR antibody (AA 801-900) (FITC)

INSRR Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN902831
  • Target See all INSRR Antibodies
    INSRR (Insulin Receptor-Related Receptor (INSRR))
    Binding Specificity
    • 14
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 801-900
    Reactivity
    • 55
    • 22
    • 6
    Human
    Host
    • 59
    • 1
    Rabbit
    Clonality
    • 58
    • 2
    Polyclonal
    Conjugate
    • 24
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INSRR antibody is conjugated to FITC
    Application
    • 43
    • 38
    • 18
    • 12
    • 12
    • 9
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain
    Isotype
    IgG
    Top Product
    Discover our top product INSRR Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    INSRR (Insulin Receptor-Related Receptor (INSRR))
    Alternative Name
    INSRR (INSRR Products)
    Synonyms
    IRR antibody, Irr antibody, Sirr antibody, MGC68585 antibody, INSRR antibody, insulin receptor related receptor antibody, insulin receptor-related receptor antibody, insulin receptor related receptor L homeolog antibody, INSRR antibody, Insrr antibody, insrr.L antibody, insrr antibody
    Background

    Synonyms: INSRR, Insulin receptor related receptor precursor, IR related receptor, IRR, Sirr, Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein beta chain, INSRR_HUMAN.

    Background: The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn?t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.

    Gene ID
    3645
    Pathways
    RTK Signaling
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