KLHL20 antibody (AA 13-100) (HRP)

Catalog No. ABIN903926

Product Details anti-KLHL20 Antibody (HRP)

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Binding Specificity: AA 13-100

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL20 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL20

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KLHL20

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Alternative Name: KLHL20 (KLHL20 Products)

Synonyms: fc33f09 antibody, zgc:66288 antibody, wu:fc33f09 antibody, khlhx antibody, kleip antibody, klhlx antibody, AI504637 antibody, D930050H05Rik antibody, Kleip antibody, mKIAA4210 antibody, KHLHX antibody, KLEIP antibody, KLHLX antibody, RP3-383J4.3 antibody, RGD1309490 antibody, kelch-like family member 20 antibody, kelch like family member 20 L homeolog antibody, kelch like family member 20 antibody, kelch-like 20 antibody, klhl20 antibody, klhl20.L antibody, KLHL20 antibody, Klhl20 antibody

Background:

Synonyms: Kelch like ECT2 interacting protein, Kelch like protein 20, Kelch like protein X, Kelch mot containing protein, Kelch-like ECT2-interacting protein, Kelch-like protein 20, Kelch-like protein X, KHLHX, KLEIP, KLH20CHUMAN, KLHL20, KLHLX, RP3-383J4.3.

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.

Gene ID: 27252