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DCAF6 antibody (AA 245-350) (Alexa Fluor 647)

DCAF6 Reactivity: Human IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN908957
  • Target See all DCAF6 Antibodies
    DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))
    Binding Specificity
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 245-350
    Reactivity
    • 40
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 2
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCAF6 antibody is conjugated to Alexa Fluor 647
    Application
    • 13
    • 12
    • 12
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NRIP
    Isotype
    IgG
    Top Product
    Discover our top product DCAF6 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))
    Alternative Name
    NRIP (DCAF6 Products)
    Synonyms
    1200006M05Rik antibody, ARCAP antibody, IQWD1 antibody, MSTP055 antibody, NRIP antibody, PC326 antibody, Iqwd1 antibody, RGD1561961 antibody, DCAF6 antibody, si:rp71-20i5.1 antibody, arcap antibody, dcaf6 antibody, iqwd1 antibody, mstp055 antibody, nrip antibody, pc326 antibody, DDB1 and CUL4 associated factor 6 antibody, ddb1 and cul4 associated factor 6 antibody, DDB1 and CUL4 associated factor 6 S homeolog antibody, DCAF6 antibody, Dcaf6 antibody, dcaf6 antibody, dcaf6.S antibody
    Background

    Synonyms: Androgen receptor complex associated protein, ARCAP, IQ mot and WD repeats 1, IQWD1v MSTP055, Nuclear receptor interaction protein, RP4 745I14.1, DCAF6_HUMAN.

    Background: WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

    Gene ID
    8204
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