PDK2 antibody (AA 315-407) (Alexa Fluor 555)

Catalog No. ABIN910590

Product Details anti-PDK2 Antibody (Alexa Fluor 555)

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Binding Specificity: AA 315-407

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDK2 antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDK2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDK2

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Alternative Name: PDK2 (PDK2 Products)

Synonyms: PDHK2 antibody, PDKII antibody, Pdk antibody, zgc:56209 antibody, PDK2 antibody, pyruvate dehydrogenase kinase 2 antibody, pyruvate dehydrogenase kinase, isoenzyme 2 antibody, pyruvate dehydrogenase kinase, isozyme 2b antibody, PDK2 antibody, Pdk2 antibody, pdk2b antibody

Background:

Synonyms: PDHK2, Pyruvate dehydrogenase kinase isoform 2, pyruvate dehydrogenase kinase, isozyme 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial, PDK2_HUMAN.

Background: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

Gene ID: 5164

Pathways: PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect