Endothelin 3 antibody (C-Term)
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- Target See all Endothelin 3 (EDN3) Antibodies
- Endothelin 3 (EDN3)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Endothelin 3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- EDN3 antibody was raised in rabbit using the C terminal of EDN3 as the immunogen
- Top Product
- Discover our top product EDN3 Primary Antibody
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- Application Notes
- Optimal conditions should be determined by the investigator.
- Comment
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EDN3 Blocking Peptide, catalog no. 33R-5011, is also available for use as a blocking control in assays to test for specificity of this EDN3 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- Endothelin 3 (EDN3)
- Alternative Name
- EDN3 (EDN3 Products)
- Synonyms
- et-3 antibody, EDN3 antibody, ET-3 antibody, ET3 antibody, HSCR4 antibody, PPET3 antibody, WS4B antibody, 114CH19 antibody, ls antibody, tmgc48 antibody, Et3 antibody, RGD1564825 antibody, preproET-3 antibody, endothelin-3 L homeolog antibody, endothelin 3 antibody, edn3.L antibody, EDN3 antibody, Edn3 antibody
- Background
- The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. Synonyms: Polyclonal EDN3 antibody, Anti-EDN3 antibody, endothelin 3 antibody, ET3 antibody, MGC15067 antibody, MGC61498 antibody.
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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