CARD17 antibody (Middle Region)

Catalog No. ABIN926695

Product Details anti-CARD17 Antibody

Target: CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD17 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CARD17 antibody was raised in rabbit using the middle region of CARD17 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

CARD17 Blocking Peptide, catalog no. 33R-5841, is also available for use as a blocking control in assays to test for specificity of this CARD17 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CARD17

Target: CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))

Alternative Name: CARD17 (CARD17 Products)

Synonyms: INCA antibody, caspase recruitment domain family member 17 antibody, CARD17 antibody

Background: As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation. Synonyms: Polyclonal CARD17 antibody, Anti-CARD17 antibody, caspase recruitment domain family, member 17 antibody, INCA antibody.