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AIF antibody (Middle Region)

AIFM1 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN926871
  • Target See all AIF (AIFM1) Antibodies
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Binding Specificity
    • 15
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 102
    • 55
    • 53
    • 22
    • 10
    • 8
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken
    Host
    • 91
    • 9
    • 2
    • 2
    Rabbit
    Clonality
    • 86
    • 17
    Polyclonal
    Conjugate
    • 69
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIF antibody is un-conjugated
    Application
    • 91
    • 39
    • 35
    • 29
    • 26
    • 15
    • 14
    • 13
    • 13
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Zebrafish (Brachydanio rerio), Chicken
    Purification
    Purified
    Immunogen
    AIFM1 antibody was raised in rabbit using the middle region of AIFM1 as the immunogen
    Top Product
    Discover our top product AIFM1 Primary Antibody
  • Application Notes
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    AIFM1 Blocking Peptide, catalog no. 33R-9594, is also available for use as a blocking control in assays to test for specificity of this AIFM1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Alternative Name
    AIFM1 (AIFM1 Products)
    Synonyms
    AIF antibody, CMTX4 antibody, COWCK antibody, COXPD6 antibody, PDCD8 antibody, CG7263 antibody, DmAIF antibody, Dmel\\CG7263 antibody, GB16024 antibody, DDBDRAFT_0187853 antibody, DDBDRAFT_0191137 antibody, DDB_0187853 antibody, DDB_0191137 antibody, aif antibody, pdcd8 antibody, AIFM1 antibody, PCD8 antibody, AIFsh2 antibody, Hq antibody, Pdcd8 antibody, mAIF antibody, Aif antibody, zgc:91994 antibody, apoptosis inducing factor mitochondria associated 1 antibody, allograft inflammatory factor 1 antibody, Apoptosis inducing factor antibody, apoptosis-inducing factor 1, mitochondrial antibody, apoptosis inducing factor antibody, apoptosis inducing factor, mitochondria associated 1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, apoptosis-inducing factor, mitochondrion-associated 1 antibody, AIFM1 antibody, AIF1 antibody, AIF antibody, LOC412212 antibody, aif antibody, aifm1 antibody, Aifm1 antibody
    Background
    AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene. Synonyms: Polyclonal AIFM1 antibody, Anti-AIFM1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, AIF antibody, MGC111425 antibody, PDCD8 antibody.
    Pathways
    Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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