14-3-3 theta antibody (N-Term)

Catalog No. ABIN926887

Product Details anti-14-3-3 theta Antibody

Target: 14-3-3 theta (YWHAQ)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Chicken, Rabbit, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 theta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Rabbit, Frog, Cow (Bovine), Chicken, Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: YWHAQ antibody was raised in rabbit using the N terminal of YWHAQ as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

YWHAQ Blocking Peptide, catalog no. 33R-8902, is also available for use as a blocking control in assays to test for specificity of this YWHAQ antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for 14-3-3 theta

Target: 14-3-3 theta (YWHAQ)

Alternative Name: YWHAQ (YWHAQ Products)

Background: YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. Synonyms: Polyclonal YWHAQ antibody, Anti-YWHAQ antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide antibody, 1C5 antibody, HS1 antibody.

Pathways: Apoptosis, Myometrial Relaxation and Contraction