Serotonin Receptor 3A antibody (N-Term)

Catalog No. ABIN926976

Product Details anti-Serotonin Receptor 3A Antibody

Target: Serotonin Receptor 3A (HTR3A)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine)

Purification: Purified

Immunogen: HTR3 A antibody was raised in rabbit using the N terminal of HTR3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HTR3A Blocking Peptide, catalog no. 33R-5161, is also available for use as a blocking control in assays to test for specificity of this HTR3A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: HTR3A (HTR3A Products)

Synonyms: MGC52789 antibody, HTR3A antibody, 5-HT3 antibody, 5HT3R antibody, HTR3 antibody, 5-HT-3 antibody, 5-HT3A antibody, 5-HT3R antibody, 5HT3 antibody, Htr3 antibody, 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic L homeolog antibody, 5-hydroxytryptamine receptor 3A antibody, 5-hydroxytryptamine (serotonin) receptor 3A antibody, htr3a.L antibody, HTR3A antibody, Htr3a antibody

Background: HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Synonyms: Polyclonal HTR3A antibody, Anti-HTR3A antibody, 5-hydroxytryptamine, serotonin receptor 3A antibody.

Pathways: Synaptic Membrane