ALDH5A1 antibody (Middle Region)

Catalog No. ABIN929281

This Rabbit Polyclonal antibody specifically detects ALDH5A1 in WB. It exhibits reactivity toward Human.

Quick Overview for ALDH5A1 antibody (Middle Region) (ABIN929281)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH5A1 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: ALDH5 A1 antibody was raised in rabbit using the middle region of ALDH5 1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ALDH5A1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this ALDH5A1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: ALDH5A1

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Polyclonal ALDH5A1 antibody, Anti-ALDH5A1 antibody, aldehyde dehydrogenase 5 family, member A1 antibody, SSADH antibody, SSDH antibody.

Pathways: Monocarboxylic Acid Catabolic Process