MCAF1 antibody (Activating Transcription Factor 7 Interacting Protein)

Details for Product anti-ATF7IP Antibody No. ABIN930992, Supplier: Log in to see
Antigen
  • ATF7IP
  • AM
  • MCAF
  • MCAF1
  • p621
  • 2610204M12Rik
  • Mcaf1
  • fa12g02
  • wu:fa12g02
  • zgc:152981
  • activating transcription factor 7 interacting protein
  • Atf7ip
  • ATF7IP
  • atf7ip
Reactivity
Human
16
5
3
2
2
2
2
Host
Mouse
12
5
Clonality (Clone)
Monoclonal ()
Application
Dot Blot (DB)
11
7
5
4
3
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen ATF7 IP antibody was raised in mouse using recombinant Human Activating Transcription Factor 7 Interacting Protein (Atf7 p)
Clone 2052C2a
Isotype IgG1
Cross-Reactivity Human
Cross-Reactivity (Details) Other species not studied.
Purification Protein G affinity chromatography
Alternative Name ATF7IP (ATF7IP Antibody Abstract)
Background ATF7IP is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9'. The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Synonyms: Monoclonal ATF7IP antibody, Anti-ATF7IP antibody, Activating transcription factor 7 interacting protein antibody, MCAF antibody, p621 antibody, FLJ10139 antibody, FLJ10688 antibody.
Research Area DNA/RNA
Application Notes Optimal conditions should be determined by the investigator.
Restrictions For Research Use only
Concentration Lot specific
Buffer ATF7 IP antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
Preservative Sodium azide
Precaution of Use This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Storage 4 °C
Storage Comment Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
Supplier Images
Western Blotting (WB) image for anti-Activating Transcription Factor 7 Interacting Protein (ATF7IP) antibody (ABIN930992) Left: ATF7IP staining. Right: Coomassie Blue staining of immunized recombinant protein.
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