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C14orf169 + NO66 antibody

C14orf169 Reactivity: Human DB Host: Mouse Monoclonal 3354C5a unconjugated
Catalog No. ABIN931094
  • Target See all C14orf169 + NO66 (C14orf169) Antibodies
    C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
    Reactivity
    • 16
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 13
    • 2
    • 1
    Mouse
    Clonality
    • 15
    • 1
    Monoclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C14orf169 + NO66 antibody is un-conjugated
    Application
    • 8
    • 2
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Cross-Reactivity
    Human
    Cross-Reactivity (Details)
    Other species not studied.
    Purification
    Protein G affinity chromatography
    Immunogen
    C14 orf169 antibody was raised in mouse using recombinant Human Chromosome 14 Open Reading Frame 169 (C14 rf169)
    Clone
    3354C5a
    Isotype
    IgG1
    Top Product
    Discover our top product C14orf169 Primary Antibody
  • Application Notes
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    C14 orf169 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Target
    C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
    Alternative Name
    C14orf169 (C14orf169 Products)
    Synonyms
    LOC453015 antibody, C10H14orf169 antibody, MAPJD antibody, NO66 antibody, ROX antibody, C14orf169 antibody, No66 antibody, im:7141580 antibody, no66 antibody, chromosome 14 open reading frame 169 antibody, ribosomal oxygenase 1 antibody, chromosome 5 open reading frame, human C14orf169 antibody, LOC453015 antibody, Bm1_08415 antibody, RIOX1 antibody, C5H14ORF169 antibody, Riox1 antibody, riox1 antibody
    Background
    C14orf169 encodes a histone demethylase that specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys 36' (H3K36me2). It also acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Synonyms: Monoclonal C14orf169 antibody, Anti-C14orf169 antibody, Chromosome 14 open reading frame 169 antibody, FLJ21802 antibody.
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