SOX12 antibody

Catalog No. ABIN932194

Product Details anti-SOX12 Antibody

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: SOX12 antibody was raised in mouse using recombinant Human Sry (Sex Determining Region Y)-Box 12

Clone: 86C2a

Isotype: IgG2a

Application Details

Application Notes: WB: 0.2-2 µg/mL, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: SOX12 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: SOX12 (SOX12 Products)

Synonyms: SOX22 antibody, sox-k1 antibody, sox-k1-a antibody, sox33 antibody, xSox-33 antibody, xSox-K1 antibody, xSox33 antibody, 2010205A02Rik antibody, SRY-box 12 antibody, SRY box 12 antibody, SRY-box 12 S homeolog antibody, SRY (sex determining region Y)-box 12 antibody, SOX12 antibody, Sox12 antibody, sox12.S antibody

Background: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. Synonyms: Monoclonal SOX12 antibody, Anti-SOX12 antibody, SRY (sex determining region Y) box 12 antibody, SOX22 antibody.