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Antibodies
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anti-alpha-1-Microglobulin/bikunin Precursor (AMBP) antibody
alpha-1-Microglobulin/bikunin Precursor (AMBP) antibody
| Antigen |
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| Synonyms |
HCP, ITI, UTI, EDC1, HI30, ITIL, IATIL, ITILC, AMBP, MGC128013, ambp, MGC64242, DKFZp470D2211 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Western Blotting (WB), Radioimmunoassay (RIA), Immunocytochemistry (ICC)
Western Blotting (WB) (21), Enzyme Immunoassay (EIA) (20), ELISA (16), Immunofluorescence (IF) (5), Radioimmunoassay (RIA) (3), ELISA (Detection) (2), Immunodiffusion (ID) (2), Immunoprecipitation (IP) (2), Affinity Chromatography (AC) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
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| Catalog no. |
ABIN93520 |
| Quantity |
200 ul |
| Price |
419.90 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Alternative name
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Alpha-1-microglobulin (AMBP)
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Immunogen
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rat alpha-1-microglobulin, full length, recombinant protein, overexpressed inbaculovirus-infected insect cells with N-terminal His-tag
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Format
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Lyophilized
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Description
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Alpha-1-microglobulin is a 27-kDa glycoprotein with immunosuppressiveproperties. A gene AMBP in the lipocalin cluster encodes alpha-1-microglobulintogether with a Kunitz-type proteinase inhibitor, bikunin. The gene is translatedinto the alpha-1-microglobulin-bikunin precursor, which is subsequently cleavedand the two proteins are secreted to the blood separately. Alpha-1-microglobulinis found in blood and in connective tissue in most organs. It is most abundant atinterfaces between the cells of the body and the environment, such as in lungs,intestine, kidneys and placenta. Alpha 1-microglobulin is an immunomodulatoryprotein with a broad spectrum of possible clinical applications and seems apromising marker for evaluation of tubular function.
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Specificity
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Predicted reactivity: mouse.
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Application Notes
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Recommended Dilution 1: 2000 (WB), 1: 6000 (RIA), 1: 5000 (ELISA), 1: 200 (IHC).
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Buffer
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Serum with 0.04% sodium azide
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Storage
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store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior toopening them to avoid any losses that might occur from lyophilized materialadhering to the cap or sides of the tubes.
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Research Area
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Proteasome
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Restrictions
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For Research Use only
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Publications
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Falkenberg, Grubb, Akerstroem: "Isolation of rat serum alpha 1-microglobulin. Identification of a complex with alpha 1-inhibitor-3, a rat alpha 2-macroglobulin homologue." in: The Journal of biological chemistry, Vol. 265, Issue 27, pp. 16150-7, 1990 (PubMed).
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Alternatives for antigen "alpha-1-Microglobulin/bikunin Precursor (AMBP)", type "Antibodies"
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Hosts
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Mouse (29), Rabbit (7), Sheep (3), Chicken (2)
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Reactivities
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Human (35), Rat (Rattus) (3), Guinea Pig (2), Mouse (Murine) (1), Rabbit (1)
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Applications
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Western Blotting (WB) (21), Enzyme Immunoassay (EIA) (20), ELISA (16), Immunofluorescence (IF) (5), Radioimmunoassay (RIA) (3), ELISA (Detection) (2), Immunodiffusion (ID) (2), Immunoprecipitation (IP) (2), Affinity Chromatography (AC) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
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