Advanced Glycation End Product (AGE) antibody

Antigen: Advanced Glycation End Product (AGE)

Clonality: Polyclonal

Host: Rabbit

Application: ELISA

Catalog no.: ABIN93627

Additional Information

Alternative name: AGE, Advanced Glycation End Products

Immunogen: Advanced Glycation End Products /BSA/HSA

Format: Liquid

Isotype: IgG  (Matching secondary antibodies)

Description: Protein A affinity purified IgG in PBS 10 mM, pH 7.3, 0.85% NaCl, 0.09% sodium azide**

Specificity: Advanced Glycation End Products (AGE), cross-reactivity BSA-AGE, HSA-AGE <1%

Application Details

Application Notes: ELISA, IHC not established , ELISA app. 1 µg/ml, (IHC 5-10 µg/ml) Positive Control: human lens, arteriosclerotic plaques

Concentration: 1 mg/ml

Buffer: Protein A affinity purified IgG in PBS 10 mM, pH 7.3, 0.85% NaCl, 0.09% sodium azide

Storage: 2-8°C

Research Area: Metabolism

Restrictions: For Research Use only

Publications

Publications: Araki N, Ueno N, Chakrabarti B et al.: "Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging." in: J Biol Chem, Vol. 267, Issue 15, pp. 10211-4, 1992 (PubMed).

Horiuchi S, Araki N, Morino Y: "Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. Evidence for the presence of a common structure." in: J Biol Chem, Vol. 266, Issue 12, pp. 7329-32, 1991 (PubMed).

Kume, Takeya, Mori et al.: "Immunohistochemical and ultrastructural detection of advanced glycation end products in atherosclerotic lesions of human aorta with a novel specific monoclonal antibody." in: The American journal of pathology, Vol. 147, Issue 3, pp. 654-67, 1995 (PubMed).

Miyata T, Oda O, Inagi R et al.: "beta 2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis." in: J Clin Invest, Vol. 92, Issue 3, pp. 1243-52, 1993 (PubMed).

Cellek, Qu, Schmidt et al.: "Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: a new insight into selective nitrergic neuropathy in diabetes." in: Diabetologia, Vol. 47, Issue 2, pp. 331-9, 2004 (PubMed).

Usta, Kendirci, Gur et al.: "The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: preventive versus curative treatment." in: The journal of sexual medicine, Vol. 3, Issue 2, pp. 242-50; discussion 250-2, 2006 (PubMed).