alpha-Methylacyl-CoA Racemase (AMACR) antibody

Antigen: alpha-Methylacyl-CoA Racemase (AMACR)

Synonyms: RACE, CBAS4, Macr1, Da1-8, Marc1, AMACR, DKFZp469O1232, amacr, MGC89832

Clonality: Monoclonal (13H4)

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN93638

Additional Information

Alternative name: AMACR (P504S)

Immunogen: Human recombinant AMACR (P504S) protein, whole sequence

Format: Liquid

Isotype: IgG

Clone: 13H4

Specificity: Human AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase

Application Details

Application Notes: The antibody is suitable for immunocytochemisty on cryostat and paraffin material. Western blotting has been described in literature, but has not been tested by us. In formaldehyde-fixed tissue unmasking of antigen by heat pre-treatment is required. ready to use Positive Control: Prostate carcinoma

Buffer: stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)

Storage: 2-8°C

Research Area: Signaling, Metabolism

Restrictions: For Research Use only

Images

Staining of prostate carcinoma with monoclonal rabbit antibody P504S Clone 13H4 (ABIN93638)

Detection in prostate carcinoma. (Gleason 3) Staining with rabbit monoclonal antibody P504S Klon 13H4

Publications

Babcook JS, Leslie KB, Olsen OA et al.: "A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities." in: Proc Natl Acad Sci U S A, Vol. 93, Issue 15, pp. 7843-8, 1996 (PubMed).

Xu, Stolk, Zhang et al.: "Identification of differentially expressed genes in human prostate cancer using subtraction and microarray." in: Cancer research, Vol. 60, Issue 6, pp. 1677-82, 2000 (PubMed).

Ferdinandusse, Denis, IJlst et al.: "Subcellular localization and physiological role of alpha-methylacyl-CoA racemase." in: Journal of lipid research, Vol. 41, Issue 11, pp. 1890-6, 2000 (PubMed).

Jiang, Woda, Rock et al.: "P504S: a new molecular marker for the detection of prostate carcinoma." in: The American journal of surgical pathology, Vol. 25, Issue 11, pp. 1397-404, 2001 (PubMed).