Mucin 16, Cell Surface Associated (MUC16) antibody

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Antigen
Synonyms CA125, Ca125, Gm1480, 1110008I14Rik, RGD1308422, MUC16
Reactivity
Human
(163), (6), (3)
Host
Mouse
(136), (39), (4), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(10), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
(108), (63), (63), (20), (16), (10), (9), (8), (5), (5), (3), (2), (2), (2), (1)
Pubmed 4 references available
Catalog no. ABIN93655
Quantity 1 mL
Price
671.55 $   Plus shipping costs $45.00
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Immunogen Partially purified Mucin-fraction of ovarian carcinoma
Clone OV185-1
Isotype IgG1
Specificity Mucin-like glycoprotein > 200 kDa containing CA125-epitope
Alternative Name CA 125
Research Area Cancer
Application Notes The antibody may be used in immunohistochemical investigation as well on cryostat section as on paraffin embedded material. The optimal working dilution is dependent of the secondary reagents and should be titrated by every individual laboratory. Good result have been found at 1 20 dilution using anti-mouse IgG-HRPO-conjugate and at 1 100 using VECTASTAIN Elite ABC. Secondary reagents In Formaldehyde-fixed tissue antigen unmasking at 96-100°C is required . Positive Control: Mucinous adenocarcinoma of the ovary
Restrictions For Research Use only
Format Liquid
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Preservative Sodium azide
Storage 4 °C
General Macri, Vasilev: "Highly elevated CA125 and tubo-ovarian abscess mimicking ovarian carcinoma." in: Gynecologic and obstetric investigation, Vol. 37, Issue 2, pp. 143-4, 1994 (PubMed).

Alagoz, Buller, Berman et al.: "What is a normal CA125 level?" in: Gynecologic oncology, Vol. 53, Issue 1, pp. 93-7, 1994 (PubMed).

Lagendijk JH, Mullink H, Van Diest PJ et al.: "Tracing the origin of adenocarcinomas with unknown primary using immunohistochemistry: differential diagnosis between colonic and ovarian carcinomas as primary sites." in: Hum Pathol, Vol. 29, Issue 5, pp. 491-7, 1998 (PubMed).

Ordóñez: "Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas." in: The American journal of surgical pathology, Vol. 22, Issue 10, pp. 1203-14, 1998 (PubMed).

Hosts (136), (39), (4), (1)
Reactivities (163), (6), (3)
Applications (108), (63), (63), (20), (16), (10), (9), (8), (5), (5), (3), (2), (2), (2), (1)
Conjugates (10), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (2), (2), (2), (2), (1), (1)
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