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Mucin 16, Cell Surface Associated (MUC16) antibody

Antigen

Mucin 16, Cell Surface Associated (MUC16)
Synonyms CA125, FLJ14303, Ca125, Gm1480, 1110008I14Rik, RGD1311421, RGD1308422, MUC16
Clonality Monoclonal (OV185-1)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
4 references available
Catalog no. ABIN93655
Quantity 1 ml
Price 671.55 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives back to top

Alternative name CA 125
Immunogen Partially purified Mucin-fraction of ovarian carcinoma
Format Liquid
Isotype IgG1
Clone OV185-1
Specificity Mucin-like glycoprotein > 200 kDa containing CA125-epitope

Application Details
Publications Alternatives back to top

Application Notes The antibody may be used in immunohistochemical investigation as well on cryostat section as on paraffin embedded material. The optimal working dilution is dependent of the secondary reagents and should be titrated by every individual laboratory. Good result have been found at 1 20 dilution using anti-mouse IgG-HRPO-conjugate and at 1 100 using VECTASTAIN Elite ABC. Secondary reagents In Formaldehyde-fixed tissue antigen unmasking at 96-100°C is required . Positive Control: Mucinous adenocarcinoma of the ovary
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Storage 2-8°C
Research Area Cancer
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Macri CI, Vasilev SA: "Highly elevated CA125 and tubo-ovarian abscess mimicking ovarian carcinoma." in: Gynecol Obstet Invest, Vol. 37, Issue 2, pp. 143-4, 1994 (PubMed).

Alagoz, Buller, Berman et al.: "What is a normal CA125 level?" in: Gynecologic oncology, Vol. 53, Issue 1, pp. 93-7, 1994 (PubMed).

Lagendijk JH, Mullink H, Van Diest PJ et al.: "Tracing the origin of adenocarcinomas with unknown primary using immunohistochemistry: differential diagnosis between colonic and ovarian carcinomas as primary sites." in: Hum Pathol, Vol. 29, Issue 5, pp. 491-7, 1998 (PubMed).

Ordonez NG: "Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas." in: Am J Surg Pathol, Vol. 22, Issue 10, pp. 1203-14, 1998 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Mucin 16, Cell Surface Associated (MUC16)", type "Antibodies"
Hosts Mouse (96), Rabbit (35), Goat (4), Sheep (1)
Reactivities Human (102), Mouse (Murine) (6), Rat (Rattus) (4), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
Applications ELISA (82), Western Blotting (WB) (43), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (39), Immunofluorescence (IF) (19), Immunohistochemistry (IHC) (15), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunoprecipitation (IP) (4), Enzyme Immunoassay (EIA) (3), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), ELISA (Capture) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (8), HRP (5), FITC (2), PE (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Internal Region (3), Extracellular Domain (2), C-Term (1)