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Ki-67 (Cell Cycle Marker) antibody

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Antigen
Reactivity
Human
Host
Mouse
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Immunogen Human nuclear Ki-67 antigen
Clone MIB-1
Isotype IgG1
Specificity Ki-67 nuclear protein
Research Area Proliferation Markers, Cell Cycle
Application Notes IHC(P) , Unmasking fluid G at 90-100°C neat Positive Control: Breast or colon carcinoma
Restrictions For Research Use only
Format Liquid
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Gerdes, Becker, Key, Cattoretti: "Immunohistological detection of tumour growth fraction (Ki-67 antigen) in formalin-fixed and routinely processed tissues." in: The Journal of pathology, Vol. 168, Issue 1, pp. 85-6, 1993 (PubMed).

Gerdes, Stein, Pileri, Rivano, Gobbi, Ralfkiaer, Nielsen, Pallesen, Bartels, Palestro: "Prognostic relevance of tumour-cell growth fraction in malignant non-Hodgkin's lymphomas." in: Lancet, Vol. 2, Issue 8556, pp. 448-9, 1987 (PubMed).

Gerdes, Schwab, Lemke, Stein: "Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation." in: International journal of cancer. Journal international du cancer, Vol. 31, Issue 1, pp. 13-20, 1983 (PubMed).