Melan A (MLANA) antibody

Antigen: Melan A (MLANA)

Synonyms: MART1, MART-1

Clonality: Monoclonal (A103)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN93788

Additional Information

Alternative name: Melan-A / MART-1

Immunogen: Recombinant Melan-A protein

Format: Liquid

Isotype: IgG1

Clone: A103

Specificity: 20-22 kDA Melan-A protein, no cross-reactivity to MAGE-1 and Tyrosinase

Application Details

Application Notes: IHC(P) , Heat pre-treatment of formalin fixed material with Unmasking Fluid G (Art.-No. DE007) is recommended. Positive Control: Melanoma

Buffer: stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)

Storage: 2-8°C

Restrictions: For Research Use only

Publications

Jungbluth AA, Busam KJ, Gerald WL et al.: "A103: An anti-melan-a monoclonal antibody for the detection of malignant melanoma in paraffin-embedded tissues." in: Am J Surg Pathol, Vol. 22, Issue 5, pp. 595-602, 1998 (PubMed).

Florell SR, Zone JJ, Gerwels JW: "Basal cell carcinomas are populated by melanocytes and Langerhans [correction of Langerhan's] cells." in: Am J Dermatopathol, Vol. 23, Issue 1, pp. 24-8, 2001 (PubMed).

Berset M, Cerottini JP, Guggisberg D et al.: "Expression of Melan-A/MART-1 antigen as a prognostic factor in primary cutaneous melanoma." in: Int J Cancer, Vol. 95, Issue 1, pp. 73-7, 2001 (PubMed).