Melanoma antibody

Details for Product No. ABIN93791, Supplier: Log in to see
Antigen
Reactivity
Human
30
3
3
2
Host
Mouse
32
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
21
11
9
6
2
2
1
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Immunogen Extract from lymph node metastases of melanoma
Clone HMB45
Isotype IgG1
Specificity Neuraminidase-sensitive glycoconjugate on the surface of human melanosomes
Research Area Cancer
Application Notes IHC(P) , Pre-treatment with pronase 0,1% or unmasking fluid G neat Positive Control: Melanoma
Restrictions For Research Use only
Format Liquid
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Kapur, Bigler, Skelly, Gown: "Anti-melanoma monoclonal antibody HMB45 identifies an oncofetal glycoconjugate associated with immature melanosomes." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 40, Issue 2, pp. 207-12, 1992 (PubMed).

Gown, Vogel, Hoak, Gough, McNutt: "Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes." in: The American journal of pathology, Vol. 123, Issue 2, pp. 195-203, 1986 (PubMed).