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Melanoma antibody

Antigen

Melanoma

Clonality Monoclonal (HMB45)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
2 references available
Catalog no. ABIN93791
Quantity 5 ml  (Variants)
Price 217.80 $   Plus shipping costs $45.00
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Additional Information

Alternative name Melanoma, HMB45
Immunogen Extract from lymph node metastases of melanoma
Format Liquid
Isotype IgG1
Clone HMB45
Specificity Neuraminidase-sensitive glycoconjugate on the surface of human melanosomes

Application Details

Application Notes IHC(P) , Pre-treatment with pronase 0,1% or unmasking fluid G neat Positive Control: Melanoma
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Storage 2-8°C
Research Area Cancer
Restrictions For Research Use only

Publications

Kapur, Bigler, Skelly et al.: "Anti-melanoma monoclonal antibody HMB45 identifies an oncofetal glycoconjugate associated with immature melanosomes." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 40, Issue 2, pp. 207-12, 1992 (PubMed).

Gown, Vogel, Hoak et al.: "Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes." in: The American journal of pathology, Vol. 123, Issue 2, pp. 195-203, 1986 (PubMed).