Tumor Protein P63 (TP63) antibody

Details for Product No. ABIN93812
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Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(35), (25), (25), (4), (4), (4), (4), (2), (2), (1)
Host
Mouse
(29), (6)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(26), (10), (8), (8), (5), (2), (1)
Pubmed 4 references available
Quantity 10 mL
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN93812
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Immunogen Recombinant p63 Protein (AA 1-205) N-terminal part of deltaNp63
Clone 4A4
Isotype IgG2a
Specificity P63 (6 Isotypes)
Alternative Name p63 Protein
Research Area Cancer, Signaling, Apoptosis/Necrosis
Application Notes IHC(P) , Pre-treatment of formaldehyde-fixed tissue with Tris-buffered EDTA solution pH 9 (Art.-No. DE006) or Unmasking Fluid G (Art.-No. DE007) 40 min at 100°C neat Positive Control: Normal prostate tissue or skin
Restrictions For Research Use only
Format Liquid
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
anti-Tumor Protein P63 (TP63) antibody Detection of p63 protein in nucleus of epidermis stained with anti-p63 antibody
General Yang, Kaghad, Wang et al.: "p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities." in: Molecular cell, Vol. 2, Issue 3, pp. 305-16, 1998 (PubMed).

Celli J, Duijf P, Hamel BC et al.: "Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome." in: Cell, Vol. 99, Issue 2, pp. 143-53, 1999 (PubMed).

Signoretti, Waltregny, Dilks et al.: "p63 is a prostate basal cell marker and is required for prostate development." in: The American journal of pathology, Vol. 157, Issue 6, pp. 1769-75, 2000 (PubMed).

Pelosi G, Pasini F, Olsen Stenholm C et al.: "p63 immunoreactivity in lung cancer: yet another player in the development of squamous cell carcinomas?" in: J Pathol, Vol. 198, Issue 1, pp. 100-9, 2002 (PubMed).

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