alpha-Methylacyl-CoA Racemase (AMACR) antibody

Antigen: alpha-Methylacyl-CoA Racemase (AMACR)

Synonyms: RACE, CBAS4, Macr1, Da1-8, Marc1, AMACR, DKFZp469O1232, amacr, MGC89832

Clonality: Monoclonal (13H4-4A4)

Host: Rabbit/Mouse Cocktail

Reactivity: Human

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN93825

Additional Information

Alternative name: PIN-Cocktail 1 P504S / p63

Immunogen: 1. Human recombinant AMACR (P504S) protein, whole sequence (for rabbit monoclonal antibody 13H4), 2. Recombinant human p63 protein aa 1-205 (for mouse monoclonal antibody 4A4)

Format: Ready to use

Isotype: IgG2a

Clone: 13H4-4A4

Description: Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 50 immunohistochemical tests (100 ul working solution / test). Use appropriate antibody diluent.

Specificity: Human AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase and human p63 nuclear protein

Application Details

Application Notes: Der Antikörper-Cocktail ist geeignet für frisches Gewebe und Paraffinschnitte. Vorbehandlung: Bei Formalin-fixiertem Material werden die Antigene durch Demaskierung mit Tris/EDTA/Citrat-Puffer pH 8 (TEC-Puffer) im Dampftopf über 30 min nachweisbar. Gebra ready to use Positive Control: Prostatic intraepithelial neoplasia

Buffer: Antibody solution in PBS buffer pH 7.3, containing BSA and sodium azide 0.09%

Storage: 2-8°C

Restrictions: For Research Use only

Publications

Publications: Jiang Z, Woda BA, Rock KL et al.: "P504S: a new molecular marker for the detection of prostate carcinoma." in: Am J Surg Pathol, Vol. 25, Issue 11, pp. 1397-404, 2001 (PubMed).

Luo, Zha, Gage et al.: "Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer." in: Cancer research, Vol. 62, Issue 8, pp. 2220-6, 2002 (PubMed).

Weinstein MH, Signoretti S, Loda M: "Diagnostic utility of immunohistochemical staining for p63, a sensitive marker of prostatic basal cells." in: Mod Pathol, Vol. 15, Issue 12, pp. 1302-8, 2002 (PubMed).