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P504S / p63 / HMW Cytokeratin antibody

Details for Product No. ABIN93826, Supplier: Login to see
Antigen
Reactivity
Human
2
Host
Rabbit/Mouse Cocktail
2
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)
2
2
Supplier
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Immunogen 1. Human recombinant AMACR (P504S) protein, whole sequence (for rabbit monoclonal antibody 13H4), 2. Recombinant human p63 protein aa 1-205 (for mouse monoclonal antibody 4A4), 3. Cytokeratin extract of human stratum corneum (for mouse monoclonal antibody 34betaE12)
Clone 13H4-4A4-34betaE12
Isotype IgG Mix
Specificity 1. Human AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase, 2. human p63 nuclear protein, and 3. high molecular weight cytokeratins (56-57 and 66-68 kDa)
Application Notes IHC, paraffin sections , TEC buffer (Tris/EDTA/Citrate) pH 8 in a pressure cooker at 100°C 20-40 minutes. ready to use Positive Control: Prostate Intraepithelial Neoplasia, prostate carc
Restrictions For Research Use only
Format Liquid
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Weinstein MH, Signoretti S, Loda M: "Diagnostic utility of immunohistochemical staining for p63, a sensitive marker of prostatic basal cells." in: Mod Pathol, Vol. 15, Issue 12, pp. 1302-8, 2002 (PubMed).

Luo, Zha, Gage et al.: "Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer." in: Cancer research, Vol. 62, Issue 8, pp. 2220-6, 2002 (PubMed).

Jiang Z, Woda BA, Rock KL et al.: "P504S: a new molecular marker for the detection of prostate carcinoma." in: Am J Surg Pathol, Vol. 25, Issue 11, pp. 1397-404, 2001 (PubMed).