P504S / p63 / HMW Cytokeratin antibody

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Rabbit/Mouse Cocktail
Clonality (Clone)
Monoclonal ()
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)
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Immunogen 1. Human recombinant AMACR (P504S) protein, whole sequence (for rabbit monoclonal antibody 13H4), 2. Recombinant human p63 protein aa 1-205 (for mouse monoclonal antibody 4A4), 3. Cytokeratin extract of human stratum corneum (for mouse monoclonal antibody 34betaE12)
Clone 13H4-4A4-34betaE12
Isotype IgG Mix
Specificity 1. Human AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase, 2. human p63 nuclear protein, and 3. high molecular weight cytokeratins (56-57 and 66-68 kDa)
Application Notes IHC, paraffin sections , TEC buffer (Tris/EDTA/Citrate) pH 8 in a pressure cooker at 100°C 20-40 minutes. ready to use Positive Control: Prostate Intraepithelial Neoplasia, prostate carc
Restrictions For Research Use only
Format Liquid
Buffer stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 ul working solution / test)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Weinstein MH,Signoretti S,Loda M: "Diagnostic utility of immunohistochemical staining for p63, a sensitive marker of prostatic basal cells." in: Mod Pathol, Vol. 15, Issue 12, pp. 1302-8, 2002 (PubMed).

Luo, Zha, Gage, Dunn, Hicks, Bennett, Ewing, Platz, Ferdinandusse, Wanders, Trent, Isaacs, De Marzo: "Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer." in: Cancer research, Vol. 62, Issue 8, pp. 2220-6, 2002 (PubMed).

Jiang Z,Woda BA,Rock KL,Xu Y,Savas L,Khan A,Pihan G,Cai F,Babcook JS,Rathanaswami P,Reed SG,Xu J,Fanger GR: "P504S: a new molecular marker for the detection of prostate carcinoma." in: Am J Surg Pathol, Vol. 25, Issue 11, pp. 1397-404, 2001 (PubMed).