S100 Calcium Binding Protein B (S100B) antibody

Antigen: S100 Calcium Binding Protein B (S100B)

Synonyms: NEF, S100, S100beta

Clonality: Monoclonal (SH-B1)

Host: Mouse

Reactivity: Cow (Bovine), Human, Cat (Feline), Rabbit, Rat (Rattus), Pig (Porcine)

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN93839

Additional Information

Alternative name: S-100 beta

Immunogen: Purified S-100beta protein from bovine brain

Format: Ready to use

Isotype: IgG1  (Matching secondary antibodies)

Clone: SH-B1

Description: Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 50 immunohistochemical tests (100 ul working solution / test). Use appropriate antibody diluent.

Specificity: S-100 beta, S-100 A (alpha/beta) and S-100 B (beta/beta), not reactive with S-100 A0 (alpha/alpha), Calmodulin, Parvalbumin and other Ca-binding proteins

Application Details

Application Notes: Der Antikörper kann auf Paraffin- oder Kryostatmaterial eingesetzt werden. Bei Kryostatmaterial ist eine kurze Fixierung der Schnitte (2 min) mit 4% gepufferter Formollösung empfehlenswert, da das S-100 Antigen sich andernfalls aus dem Gewebe lösen kann. neat Positive Control: Skin, myelinated nerves

Buffer: 5 ml phosphate buffered antibody solution containing BSA and sodium azide (0.09%) as preservative. Volume sufficient for 50 IHC stainings.

Storage: 2-8°C

Restrictions: For Research Use only

Images

Epidermis stained with anti-S100 beta antibody

Publications

Publications: Winek, Scheithauer, Wick: "Meningioma, meningeal hemangiopericytoma (angioblastic meningioma), peripheral hemangiopericytoma, and acoustic schwannoma. A comparative immunohistochemical study." in: The American journal of surgical pathology, Vol. 13, Issue 4, pp. 251-61, 1989 (PubMed).

Moore: "A soluble protein characteristic of the nervous system." in: Biochemical and biophysical research communications, Vol. 19, Issue 6, pp. 739-44 (PubMed).

Lauriola, Michetti, Sentinelli et al.: "Detection of S-100 labelled cells in nasopharyngeal carcinoma." in: Journal of clinical pathology, Vol. 37, Issue 11, pp. 1235-8, 1985 (PubMed).

Kindblom, Lodding, Rosengren et al.: "S-100 protein in melanocytic tumors. An immunohistochemical investigation of benign and malignant melanocytic tumors and metastases of malignant melanoma and a characterization of the antigen in comparison to human brain." in: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, Vol. 92, Issue 4, pp. 219-30, 1984 (PubMed).