SLC3A2 antibody (Biotin)

Catalog No. ABIN94256

Product Details anti-SLC3A2 Antibody (Biotin)

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC3A2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: The antibody MEM-108 reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells, it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.

Cross-Reactivity (Details): Human

Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogen: RAJI human Burkitt's lymphoma cell line

Clone: MEM-108

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 3 μg/mL.

Comment:

The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.
Avoid prolonged exposure to light.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for SLC3A2

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Alternative Name: CD98 (SLC3A2 Products)

Synonyms: 4F2 antibody, 4F2HC antibody, 4T2HC antibody, CD98 antibody, CD98HC antibody, MDU1 antibody, NACAE antibody, Mdu1 antibody, MGC53951 antibody, slc3a2 antibody, MGC53965 antibody, SLC3A2 antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mgp-2hc antibody, fc65h12 antibody, wu:fc65h12 antibody, id:ibd1327 antibody, sb:cb519 antibody, wu:fe14a07 antibody, wu:fq18d12 antibody, zgc:55813 antibody, solute carrier family 3 member 2 antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2a antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2b antibody, SLC3A2 antibody, Slc3a2 antibody, slc3a2.L antibody, slc3a2.S antibody, slc3a2a antibody, slc3a2b antibody

Background: Solute carrier family 7 member 5,CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.,4F2, MDU1, 4F2HC, 4T2HC, NACAE, SLC3A2

Gene ID: 8140

UniProt: Q01650