HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) antibody

Details for Product No. ABIN94369, Supplier: Log in to see
Antigen
  • MHC-G
  • B-F
  • B-F-S04
  • B-F-S05
  • B-F-S06
  • B-F-S07
  • B-FI
  • B-FIV
  • BF2
  • BFa2
  • BFw-03
  • BFw-05
  • BFz-01
  • major histocompatibility complex, class I, G
  • MHC BF1 class I
  • HLA-G
  • BF1
Alternatives
anti-Human HLA Class I Histocompatibility Antigen, alpha Chain G antibody for ELISA
Reactivity
Human
508
41
9
9
1
1
1
1
Host
Mouse
412
73
26
6
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
52
52
37
27
12
9
9
9
9
9
9
9
9
9
9
8
8
8
7
5
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP)
303
294
279
156
133
129
118
114
79
22
21
14
8
8
5
3
3
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Recombinant human HLA-G refolded with beta2-microglobulin and peptide.
Clone MEM-G-9
Isotype IgG1
Specificity The antibody MEM-G/9 reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. Reactivity with HLA-G3 was also reported.
The antibody MEM-G/9 is standard reagent thoroughly validated during 3rd International Conference on HLA-G (Paris, 2003).
No Cross-Reactivity Mouse (Murine)
Purification Purified by protein A
Purity > 95 % (by SDS-PAGE)
Alternative Name HLAG (HLAG Antibody Abstract)
Research Area Major Histocompatibility Complex (MHC)
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Flow Cytometry (FACS) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) antibody (ABIN94369) Double surface staining of HLA-G1 transfectants (viable cells gate) using anti-human ...
Immunofluorescence (IF) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) antibody (ABIN94369) Immunofluorescence staining of HLA-G1 transfectants (LCL-HLA-G1) using anti-human HLA...
Immunoprecipitation (IP) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) antibody (ABIN94369) Immunoprecipitation of HLA-G from HLA-G1 transfectants (LCL-HLA-G1) by anti-human HLA...
Product cited in: Zhao, Teklemariam, Hantash: "Reassessment of HLA-G isoform specificity of MEM-G/9 and 4H84 monoclonal antibodies." in: Tissue antigens, Vol. 80, Issue 3, pp. 231-8, 2012 (PubMed).

Gauster, Berghold, Moser, Orendi, Siwetz, Huppertz: "Fibulin-5 expression in the human placenta." in: Histochemistry and cell biology, Vol. 135, Issue 2, pp. 203-13, 2011 (PubMed).

Giuliani, Fleury, Vernochet, Ketroussi, Clay, Azzarone, Lataillade, Durrbach: "Long-lasting inhibitory effects of fetal liver mesenchymal stem cells on T-lymphocyte proliferation." in: PLoS ONE, Vol. 6, Issue 5, pp. e19988, 2011 (PubMed).

Gonzalez, Alegre, Arroyo, LeMaoult, Echeveste: "Identification of circulating nonclassic human leukocyte antigen G (HLA-G)-like molecules in exudates." in: Clinical chemistry, Vol. 57, Issue 7, pp. 1013-22, 2011 (PubMed).

Ongaro, Stignani, Pellati, Melchiorri, Massari, Caruso, De Mattei, Caruso, Baricordi, Rizzo: "Human leukocyte antigen-G molecules are constitutively expressed by synovial fibroblasts and upmodulated in osteoarthritis." in: Human immunology, Vol. 71, Issue 4, pp. 342-50, 2010 (PubMed).

Shaikly, Shakhawat, Withey, Morrison, Taranissi, Dealtry, Jabeen, Cherry, Fernuandez: "Cell bio-imaging reveals co-expression of HLA-G and HLA-E in human preimplantation embryos." in: Reproductive biomedicine online, Vol. 20, Issue 2, pp. 223-233, 2010 (PubMed).

Morandi, Ferretti, Bocca, Prigione, Raffaghello, Pistoia: "A novel mechanism of soluble HLA-G mediated immune modulation: downregulation of T cell chemokine receptor expression and impairment of chemotaxis." in: PLoS ONE, Vol. 5, Issue 7, pp. e11763, 2010 (PubMed).

Alegre, Howangyin, Favier, Baudhuin, Lesport, Daouya, Gonzalez, Carosella, Lemaoult: "Membrane redistributions through multi-intercellular exchanges and serial trogocytosis." in: Cell research, Vol. 20, Issue 11, pp. 1239-51, 2010 (PubMed).

López, Alegre, LeMaoult, Carosella, González: "Regulatory role of tryptophan degradation pathway in HLA-G expression by human monocyte-derived dendritic cells." in: Molecular immunology, Vol. 43, Issue 14, pp. 2151-60, 2006 (PubMed).

Gonen-Gross, Achdout, Arnon, Gazit, Stern, Horejsí, Goldman-Wohl, Yagel, Mandelboim: "The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, 2005 (PubMed).

Menier, Saez, Horejsi, Martinozzi, Krawice-Radanne, Bruel, Le Danff, Reboul, Hilgert, Rabreau, Larrad, Pla, Carosella, Rouas-Freiss: "Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules." in: Human immunology, Vol. 64, Issue 3, pp. 315-26, 2003 (PubMed).

Fuzzi, Rizzo, Criscuoli, Noci, Melchiorri, Scarselli, Bencini, Menicucci, Baricordi: "HLA-G expression in early embryos is a fundamental prerequisite for the obtainment of pregnancy." in: European journal of immunology, Vol. 32, Issue 2, pp. 311-5, 2002 (PubMed).

Lozano, González, Kindelán, Rouas-Freiss, Caballos, Dausset, Carosella, Peña: "Monocytes and T lymphocytes in HIV-1-positive patients express HLA-G molecule." in: AIDS, Vol. 16, Issue 3, pp. 347-51, 2002 (PubMed).

Pangault, Le Friec, Caulet-Maugendre, Léna, Amiot, Guilloux, Onno, Fauchet: "Lung macrophages and dendritic cells express HLA-G molecules in pulmonary diseases." in: Human immunology, Vol. 63, Issue 2, pp. 83-90, 2002 (PubMed).

Fournel, Huc, Aguerre-Girr, Solier, Legros, Praud-Brethenou, Moussa, Chaouat, Berrebi, Bensussan, Lenfant, Le Bouteiller: "Comparative reactivity of different HLA-G monoclonal antibodies to soluble HLA-G molecules." in: Tissue antigens, Vol. 55, Issue 6, pp. 510-8, 2000 (PubMed).

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