MLL2 antibody (AA 1487-1586)

Catalog No. ABIN948660

Product Details anti-MLL2 Antibody

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Binding Specificity: AA 1487-1586

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Mouse monoclonal antibody raised against a partial recombinant MLL2.

Sequence: SKLEGMFPAY LQEAFFGKEL LDLSRKALFA VGVGRPSFGL GTPKAKGDGG SERKELPTSQ KGDDGPDIAD EESRGLEGKA DTPGPEDGGV KASPVPSDPE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MLL2 (NP_003473.1, 1487 a.a. ~ 1586 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2E1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MLL2 antibody (ABIN948660)

Micale, Augello, Maffeo, Selicorni, Zucchetti, Fusco, De Nittis, Pellico, Mandriani, Fischetto, Boccone, Silengo, Biamino, Perria, Sotgiu, Serra, Lapi, Neri, Ferlini, Cavaliere, Chiurazzi, Monica et al.: "Molecular analysis, pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients. ..." in: Human mutation, Vol. 35, Issue 7, pp. 841-50, (2014) (PubMed).

Target Details for MLL2

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Alternative Name: MLL2 (MLL2 Products)

Background: Full Gene Name: myeloid/lymphoid or mixed-lineage leukemia 2
Synonyms: AAD10,ALR,CAGL114,MLL4,TNRC21

Gene ID: 8085

NCBI Accession: NM_003482

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect