HSD17B3 antibody (Middle Region)

Catalog No. ABIN950183

Product Details anti-HSD17B3 Antibody

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Binding Specificity: AA 96-126, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human 17-beta-HSD3 / HSD17B3 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 96~126 amino acids from the Central region of human 17-beta-HSD3 / HSD17B3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Alternative Name: 17-beta-HSD3 / HSD17B3 (HSD17B3 Products)

Synonyms: EDH17B3 antibody, SDR12C2 antibody, hydroxysteroid (17-beta) dehydrogenase 3 antibody, hydroxysteroid 17-beta dehydrogenase 3 antibody, Hsd17b3 antibody, HSD17B3 antibody

Background: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.Synonyms: 17-beta-hydroxysteroid dehydrogenase type 3, EDH17B3, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3

Molecular Weight: 34516 Da

Gene ID: 3293

NCBI Accession: NP_000188

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis