ABCC3 antibody (Middle Region)

Catalog No. ABIN950200

Product Details anti-ABCC3 Antibody

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Binding Specificity: AA 906-933, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ABCC3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 906-933 amino acids from the Central region of human ABCC3.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ABCC3

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Alternative Name: ABCC3 / CMOAT2 / MRP3 (ABCC3 Products)

Synonyms: ABC31 antibody, EST90757 antibody, MLP2 antibody, MOAT-D antibody, MRP3 antibody, cMOAT2 antibody, 1700019L09Rik antibody, Mlp2 antibody, Mrp3 antibody, ATP binding cassette subfamily C member 3 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 3 antibody, ABCC3 antibody, Abcc3 antibody

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.Synonyms: Canalicular multispecific organic anion transporter 2, MLP2, Multidrug resistance-associated protein 3

Gene ID: 8714

NCBI Accession: NP_001137542