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Abcd2 antibody (C-Term)

Abcd2 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN950203
  • Target See all Abcd2 Antibodies
    Abcd2 (ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2))
    Binding Specificity
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 552-582, C-Term
    Reactivity
    • 20
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 20
    • 1
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This Abcd2 antibody is un-conjugated
    Application
    • 21
    • 13
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to ABCD2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 552-582 amino acids from the C-terminal region of human ABCD2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product Abcd2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Abcd2 (ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2))
    Alternative Name
    ABCD2 / ALDR (Abcd2 Products)
    Synonyms
    DDBDRAFT_0214891 antibody, DDBDRAFT_0219834 antibody, DDB_0214891 antibody, DDB_0219834 antibody, ABC39 antibody, ALDL1 antibody, ALDR antibody, ALDRP antibody, hALDR antibody, ATP binding cassette subfamily D member 2 antibody, ABC transporter D family protein antibody, ATP-binding cassette sub-family D member 2 antibody, ATP-binding cassette, sub-family D (ALD), member 2 antibody, ABCD2 antibody, abcD2 antibody, LOC100549247 antibody, abcd2 antibody, LOC100640478 antibody, Abcd2 antibody
    Background
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.Synonyms: ALD1, ALDL1, ALDRP, ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein
    Gene ID
    225
    NCBI Accession
    NP_005155
    Pathways
    Monocarboxylic Acid Catabolic Process
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