ABI2 antibody (Abl-Interactor 2) (N-Term)

Details for Product anti-ABI2 Antibody No. ABIN950216, Supplier: Log in to see
Antigen
  • ABI-2
  • ABI2B
  • AIP-1
  • AblBP3
  • SSH3BP2
  • argBPIA
  • argBPIB
  • 8430425M24Rik
  • AI839867
  • C130078H13
  • abl-interactor 2
  • ABI2
  • abi2
  • Abi2
Epitope
N-Term, AA 1-30
17
14
7
3
2
1
Reactivity
Human, Mouse (Murine)
42
20
11
3
3
2
2
2
2
1
1
1
1
Host
Rabbit
38
4
Clonality
Polyclonal
Conjugate
This ABI2 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
41
21
15
11
4
2
1
1
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ABI2
Isotype Ig
Specificity This antibody reacts to ABI2.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity chromatography on Protein A
Alternative Name ABI2 (ABI2 Antibody Abstract)
Background ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May be involved in cytoskeletal reorganization. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.Synonyms: ARGBPIA, Abelson interactor 2, Abl interactor 2, Abl-binding protein 3, Arg-binding protein 1, argBPIA
Gene ID 10152
NCBI Accession NP_005750
Research Area Cancer
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ABI2 antibody (Abl-Interactor 2) (N-Term) (ABIN950216) ABI2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35 µg/lane)...
Western Blotting (WB) image for anti-ABI2 antibody (Abl-Interactor 2) (N-Term) (ABIN950216) ABI2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35 µg/lan...
Background publications Ryu, Echarri, Li, Pendergast: "Regulation of cell-cell adhesion by Abi/Diaphanous complexes." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1735-48, 2009 (PubMed).

Kano, Miyajima, Fukuda, Hatakeyama: "Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2." in: Cancer research, Vol. 68, Issue 14, pp. 5572-80, 2008 (PubMed).

Li, Clough, Sun, Yu, Abbott, Hogan, Dai: "Bcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway." in: Journal of cell science, Vol. 120, Issue Pt 8, pp. 1436-46, 2007 (PubMed).

Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).