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Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody

Details for Product No. ABIN950242, Supplier: Log in to see
Antigen
  • hACTE-III
  • HNAACTE
  • hTE
  • PTE-1
  • PTE-2
  • Pte1
  • PTE1
  • PTE2
  • zgc:101691
Epitope
AA 290-319, C-Term
17
17
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
53
22
19
2
Host
Rabbit
47
6
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
27
20
15
11
11
5
3
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 290~319 amino acids from the C-terminal region of human ACOT8
Isotype Ig
Specificity This antibody reacts to ACOT8.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity chromatography on Protein A
Alternative Name ACOT8 (ACOT8 Antibody Abstract)
Background Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.Synonyms: ACTEIII, Acyl-CoA thioesterase 8, Choloyl-coenzyme A thioesterase, HIV-Nef-associated acyl-CoA thioesterase, PTE-2, PTE1, PTE2, Peroxisomal acyl-coenzyme A thioester hydrolase 1, Peroxisomal long-chain acyl-CoA thioesterase 1, Thioesterase II
Gene ID 10005
NCBI Accession NP_005460
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody (ABIN950242) ACOT8 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (bottom histogram...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody (ABIN950242) Formalin-fixed and paraffin-embedded human Prostate carcinoma reacted with ACOT8 Anti...
Western Blotting (WB) image for anti-Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody (ABIN950242) Western blot analysis of ACOT8 Antibody (C-term) in mouse liver tissue lysates (35 µg...
Background publications Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, 2009 (PubMed).

Product cited in: Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).