anti-Afamin antibody (AFM) (N-Term)

Details for Product anti-AFM Antibody No. ABIN950291
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Antigen
Synonyms AFM, ALB2, ALBA, ALF, Alf, alpha-Alb
Epitope
N-Term, AA 55-85
(12), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(56), (21), (15), (3), (3), (1), (1), (1)
Host
Rabbit
(46), (13), (3), (1)
Clonality
Polyclonal
Conjugate
This Afamin antibody is un-conjugated
(6), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(49), (32), (10), (10), (8), (7), (7), (6), (3), (1), (1), (1)
Pubmed 6 references available
Quantity 0.4 mL
Shipping to United States ( )
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Request Want additional data for this product?

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Immunogen KLH conjugated synthetic peptide between 55~85 amino acids from the N-terminal region of human AFM
Isotype Ig
Specificity This antibody reacts to Afamin.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name Afamin / AFM (AFM Antibody Abstract)
Background AFM is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.Synonyms: ALB2, ALBA, Alpha-albumin
Gene ID 173
NCBI Accession NP_001124
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Dieplinger, Ankerst, Burges et al.: "Afamin and apolipoprotein A-IV: novel protein markers for ovarian cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 4, pp. 1127-33, 2009 (PubMed).

Kratzer, Bernhart, Wintersperger et al.: "Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier." in: Journal of neurochemistry, Vol. 108, Issue 3, pp. 707-18, 2009 (PubMed).

Ramachandran, Boontheung, Xie et al.: "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry." in: Journal of proteome research, Vol. 5, Issue 6, pp. 1493-503, 2006 (PubMed).

Liu, Qian, Gritsenko et al.: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, 2005 (PubMed).

Hu, Malone, Fagan et al.: "Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 12, pp. 2000-9, 2005 (PubMed).

Bunkenborg, Pilch, Podtelejnikov et al.: "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry." in: Proteomics, Vol. 4, Issue 2, pp. 454-65, 2004 (PubMed).

Validation Images
Catalog No. ABIN950291
357.50 $
Plus shipping costs $45.00
Quantity
Price
0.4 mL
357.50 $

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