PRKAG1 antibody (N-Term)

Catalog No. ABIN950401

Product Details anti-PRKAG1 Antibody

Target: PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Binding Specificity: AA 5-33, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAG1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PRKAG1.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human PRKAG1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PRKAG1

Target: PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Alternative Name: AMPK gamma-1 Chain / AMPKg (PRKAG1 Products)

Synonyms: MGC68503 antibody, zgc:63896 antibody, wu:fa94d09 antibody, wu:fd12h04 antibody, AMPKG antibody, Prkaac antibody, Prkga1 antibody, AA571379 antibody, BB036179 antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit antibody, protein kinase AMP-activated non-catalytic subunit gamma 1 antibody, prkag1.S antibody, prkag1 antibody, PRKAG1 antibody, Prkag1 antibody

Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Synonyms: 5'-AMP-activated protein kinase subunit gamma-1, PRKAG1

Molecular Weight: 37579 Da

Gene ID: 5571

NCBI Accession: NP_001193638

Pathways: AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect