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ATP6V1A antibody (Middle Region)

ATP6V1A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN950568
  • Target See all ATP6V1A Antibodies
    ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 447-477, Middle Region
    Reactivity
    • 33
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 5
    Rabbit
    Clonality
    • 29
    • 5
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    This ATP6V1A antibody is un-conjugated
    Application
    • 29
    • 20
    • 17
    • 6
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts to ATP6V1A.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 447~477 amino acids from the Central region of human ATP6V1A
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATP6V1A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) sodium azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))
    Alternative Name
    ATP6V1A (ATP6V1A Products)
    Synonyms
    ATP6A1 antibody, ATP6V1A1 antibody, HO68 antibody, VA68 antibody, VPP2 antibody, Vma1 antibody, AI647066 antibody, Atp6a1 antibody, Atp6a2 antibody, Atp6v1a1 antibody, ATP6V1A antibody, atp6v1al antibody, zgc:63516 antibody, An02g10440 antibody, AO090102000349 antibody, vacuolar ATP synthase subunit A antibody, atp6a1 antibody, atp6v1a1 antibody, ho68 antibody, v1a antibody, va68 antibody, vma1 antibody, vpp2 antibody, CG12403 antibody, Dmel\CG12403 antibody, V-ATPase antibody, Vha antibody, Vha-68-1 antibody, Vha68 antibody, vha67-2 antibody, vha68-1 antibody, ATPase H+ transporting V1 subunit A antibody, ATPase, H+ transporting, lysosomal V1 subunit A antibody, ATPase, H+ transporting, lysosomal, V1 subunit Aa antibody, v-type proton ATPase catalytic subunit A antibody, vacuolar ATP synthase subunit A antibody, ATPase H+ transporting V1 subunit A L homeolog antibody, vacuolar proton pump 3 antibody, Vacuolar H[+] ATPase 68kD subunit 1 antibody, ATP6V1A antibody, Atp6v1a antibody, atp6v1aa antibody, ANI_1_1468024 antibody, AOR_1_602134 antibody, VHA-A antibody, atp6v1a.L antibody, vpp3 antibody, Vha68-1 antibody
    Background
    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues.Synonyms: ATP6A1, ATP6V1A1, V-ATPase 69 kDa subunit, V-ATPase subunit A, V-type proton ATPase catalytic subunit A, VPP2, Vacuolar ATPase isoform VA68, Vacuolar proton pump subunit alpha
    Gene ID
    523
    NCBI Accession
    NP_001681
    Pathways
    Transition Metal Ion Homeostasis, Proton Transport, SARS-CoV-2 Protein Interactome
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