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BAG5 antibody (BCL2-Associated Athanogene 5) (N-Term)

Details for Product anti-BAG5 Antibody No. ABIN950599, Supplier: Log in to see
Antigen
  • BAG5
  • zgc:114117
  • bag-5
  • BAG-5
  • 1600025G07Rik
  • 4930405J06Rik
Epitope
N-Term, AA 20-50
37
24
15
11
7
6
2
2
2
2
1
1
1
1
Reactivity
Human
139
33
32
5
5
3
Host
Rabbit
87
45
10
Clonality
Polyclonal
Conjugate
This BAG5 antibody is un-conjugated
9
9
9
5
5
5
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
106
70
15
11
9
8
5
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human BAG5
Isotype Ig
Specificity This antibody reacts to BAG5.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name BAG5 (BAG5 Antibody Abstract)
Background BAG5 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
Gene ID 9529
NCBI Accession NP_001015048
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-BAG5 antibody (BCL2-Associated Athanogene 5) (N-Term) (ABIN950599) BAG5 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35µg/lane)....
Background publications Zhou, Deng, Xia et al.: "Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition." in: Nature cell biology, Vol. 6, Issue 10, pp. 931-40, 2004 (PubMed).

Takayama, Xie, Reed: "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 781-6, 1999 (PubMed).

Höhfeld, Jentsch: "GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1." in: The EMBO journal, Vol. 16, Issue 20, pp. 6209-16, 1997 (PubMed).