BCLAF1 antibody (C-Term)

Catalog No. ABIN950638

Product Details anti-BCLAF1 Antibody

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Binding Specificity: AA 658-688, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to BCLAF1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 658-688 amino acids from the C-terminal region of human BCLAF1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1 / BTF (BCLAF1 Products)

Synonyms: Aa2-041 antibody, Fam54a antibody, Mtfr2 antibody, 2610102K23Rik antibody, 2700025J07Rik antibody, 2810454G14Rik antibody, 5730534O06Rik antibody, AI450190 antibody, AW556225 antibody, Btf antibody, mKIAA0164 antibody, btf antibody, bk211l9.1 antibody, BCLAF1 antibody, DKFZp468F0113 antibody, BTF antibody, bK211L9.1 antibody, BCL2-associated transcription factor 1 antibody, BCL2 associated transcription factor 1 antibody, mitochondrial fission regulator 2 antibody, Bclaf1 antibody, BCLAF1 antibody, bclaf1 antibody, MTFR2 antibody

Background: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Aa2-041, Bcl-2-associated transcription factor 1, KIAA0164

Gene ID: 9774

NCBI Accession: NP_001070908

Pathways: Positive Regulation of Response to DNA Damage Stimulus