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CRYBA1 antibody (Middle Region)

CRYBA1 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN950651
  • Target See all CRYBA1 Antibodies
    CRYBA1 (Crystallin, beta A1 (CRYBA1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    AA 111-141, Middle Region
    Reactivity
    • 39
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 40
    • 1
    Rabbit
    Clonality
    • 41
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRYBA1 antibody is un-conjugated
    Application
    • 37
    • 21
    • 14
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human and Mouse Beta-crystallin A3.
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 111-141 amino acids from the Central region of Human CRYBA1. Genename: CRYBA1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CRYBA1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CRYBA1 (Crystallin, beta A1 (CRYBA1))
    Alternative Name
    beta-Crystallin A3 (CRYBA1 Products)
    Synonyms
    CRYB1 antibody, CTRCT10 antibody, BA3/A1 antibody, Cryb antibody, BA3A1C antibody, beta-A3 antibody, cryba1 antibody, zgc:92688 antibody, CRYBA3 antibody, cryb1 antibody, zgc:92720 antibody, crystallin beta A1 antibody, crystallin, beta A1 antibody, crystallin, beta A1a antibody, crystallin beta A1 L homeolog antibody, crystallin, beta A1b antibody, CRYBA1 antibody, Cryba1 antibody, cryba1a antibody, cryba1.L antibody, cryba1 antibody, cryba1b antibody
    Background
    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'Synonyms: CRYB1, CRYBA1
    Molecular Weight
    25150 Da
    Gene ID
    1411
    NCBI Accession
    NP_005199
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